STAT1 Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Produktgrößen
1 Vial
£4481,00
14-113ACL-1VIAL
Über dieses Produkt
- SKU:
- 14-113ACL
- Weitere Details:
- The STAT1 Leeporter™ Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the interferon (IFN) gamma activation sequence-based STAT1 response element; so that the cell line is designed to measure the transcriptional activity of STAT1. As a transcription factor; Signal Transducer and Activator of Transcription 1 (STAT1) is activated through phosphorylation at tyrosine 701 in response to various cytokines and growth factors such as IFN-alpha; IFN-gamma; IL-6; EGF and PDGF. The phosphorylated STAT1 forms homodimers or heterodimers with STAT3; and the dimers translocate to nucleus in which DNA binding/promoter induction occurs. The STAT1 induction by IFN-gamma is shown in Figure 1.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Immediately upon receipt; store in liquid nitrogen.
- Hersteller:
- Abeomics
- Typ:
- Cells:Cell Lines
- Datenblatt des Herstellers:14-113ACL_STAT3_RAW264.7.png