Anti-GPC3 antibody(163D11); IgG1 Chimeric mAb
Produktgrößen
10μg
£492,00
12-9625-10UG
100μg
£801,00
12-9625-100UG
Über dieses Produkt
- SKU:
- 12-9625
- Zusätzliche Namen:
- DGSX;GTR2-2;MXR7;OCI-5;SDYS;SGB;SGBS;SGBS1
- translate.label.attr.clone:
- 163D11
- Klonalität:
- Monoclonal
- Weitere Details:
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26; and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome; also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Sep 2009] References： Fu Ying;Urban Daniel J;Nani Roger R et al. Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.[J] .Hepatology; 2019; 70: 563-576. Zhang Yi-Fan;Ho Mitchell;Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.[J] .Sci Rep; 2016; 6: 33878.
- Host:
- Rabbit
- Isotyp:
- Rabbit/Human Fc chimeric IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php