Anti-PDL1 antibody(23D8); IgG1 Chimeric mAb
Produktgrößen
10μg
£492,00
12-9624-10UG
100μg
£801,00
12-9624-100UG
Über dieses Produkt
- SKU:
- 12-9624
- Zusätzliche Namen:
- PD-L1;CD274;B7-H1;PDCD1L1;PDCD1LG1
- translate.label.attr.clone:
- 23D8
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells; such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue; this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments; this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies; including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Isotyp:
- Rabbit/Human Fc chimeric IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php