Biotinylated Anti-Dxd antibody(1E6); Rabbit mAb
Produktgrößen
10 µg
£526,00
12-9553B-10UG
100 µg
£1002,00
12-9553B-100UG
Über dieses Produkt
- SKU:
- 12-9553B
- Zusätzliche Namen:
- N.A.
- translate.label.attr.clone:
- 1E6
- Klonalität:
- Monoclonal
- Weitere Details:
- Dxd is a potent anti-cancer drug; acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA; impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs); with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.
- Host:
- Rabbit
- Isotyp:
- IgG
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php