Anti-FLT3 antibody(19A5); IgG1 Chimeric mAb
Produktgrößen
10 µg
£490,00
12-9513-10UG
100 µg
£801,00
12-9513-100UG
Über dieses Produkt
- SKU:
- 12-9513
- Zusätzliche Namen:
- Flt-3;Flk-2;STK-1;CD135;FLK2;FLT-3
- translate.label.attr.clone:
- 19A5
- Klonalität:
- Monoclonal
- Weitere Details:
- Description :Anti-FLT3 antibody(19A5); IgG1 Chimeric mAb Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2); STK-1(Stem cell tyrosine kinase 1); CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation; proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1; and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases; including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.
- Host:
- Rabbit
- Isotyp:
- Rabbit/Human Fc chimeric IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg