Anti-CCR1 antibody(DMC465); IgG1 Chimeric mAb
Produktgrößen
10 µg
£490,00
12-9441-10UG
100 µg
£801,00
12-9441-100UG
Über dieses Produkt
- SKU:
- 12-9441
- Zusätzliche Namen:
- CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
- translate.label.attr.clone:
- DMC465
- Klonalität:
- Monoclonal
- Weitere Details:
- Description :Anti-CCR1 antibody(DMC465); IgG1 Chimeric mAb This gene encodes a member of the beta chemokine receptor family; which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha); regulated on activation normal T expressed and secreted protein (RANTES); monocyte chemoattractant protein 3 (MCP-3); and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response; and susceptibility to virus and parasite. This gene and other chemokine receptor genes; including CCR2; CCRL2; CCR3; CCR5 and CCXCR1; are found to form a gene cluster on chromosome 3p. [provided by RefSeq; Jul 2008]
- Host:
- Rabbit
- Isotyp:
- Rabbit/Human Fc chimeric IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg