Anti-TNFSF15 antibody(DMC464); IgG1 Chimeric mAb
Produktgrößen
10 µg
£490,00
12-9440-10UG
100 µg
£801,00
12-9440-100UG
Über dieses Produkt
- SKU:
- 12-9440
- Zusätzliche Namen:
- TL1; VEGI
- translate.label.attr.clone:
- DMC464
- Klonalität:
- Monoclonal
- Weitere Details:
- Description :Anti-TNFSF15 antibody(DMC464); IgG1 Chimeric mAbThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells; but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21:DR6. It can activate NF-kappaB and MAP kinases; and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation; and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Feb 2011]
- Host:
- Rabbit
- Isotyp:
- Rabbit/Human Fc chimeric IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg