Anti-PD-L1 antibody(DM123); Rabbit mAb
Produktgrößen
100 µg
£801,00
12-9297-100UG
Über dieses Produkt
- SKU:
- 12-9297
- Zusätzliche Namen:
- PDL1; CD274; B7-H1; PDCD1L1; PDCD1LG1
- translate.label.attr.clone:
- DM123
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells; such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue; this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments; this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies; including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
