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Antikörper

Biotinylated Anti-IL5RA antibody(DMC393); IgG1 Chimeric mAb

Produktgrößen
10 µg
£526,00
12-9246B-10UG
100 µg
£1002,00
12-9246B-100UG
Über dieses Produkt
SKU:
12-9246B
Zusätzliche Namen:
IL5Ra;CD125;IL-5 R alpha
translate.label.attr.clone:
DMC393
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3); colony stimulating factor 2 (CSF2:GM-CSF); and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding; and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin); which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Host:
Rabbit
Isotyp:
IgG1
Aufreinigung:
Purified from cell culture supernatant by affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody