Biotinylated Anti-IL4RA antibody(DMC284); IgG1 Chimeric mAb
Produktgrößen
10 µg
£526,00
12-9227B-10UG
100 µg
£1002,00
12-9227B-100UG
Über dieses Produkt
- SKU:
- 12-9227B
- Zusätzliche Namen:
- CD124; IL-4RA; IL4RA
- translate.label.attr.clone:
- DMC284
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes the alpha chain of the interleukin-4 receptor; a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein; and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy; a condition that can manifest itself as allergic rhinitis; sinusitus; asthma; or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Isotyp:
- IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php