Anti-SELPLG antibody(DMC283); IgG1 Chimeric mAb
Produktgrößen
100 µg
£801,00
12-9226-100UG
Über dieses Produkt
- SKU:
- 12-9226
- Zusätzliche Namen:
- PSGL-1;PSGL1;CD162;SELPLG;Selectin P ligand
- translate.label.attr.clone:
- DMC283
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-; E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such; this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications; tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans; for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg