Anti-PCSK9 antibody(DMC222); IgG1 Chimeric mAb
Produktgrößen
100 µg
£801,00
12-9206-100UG
Über dieses Produkt
- SKU:
- 12-9206
- Zusätzliche Namen:
- FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9
- translate.label.attr.clone:
- DMC222
- Klonalität:
- Monoclonal
- Weitere Details:
- This gene encodes a member of the subtilisin-like proprotein convertase family; which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver; intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg