Recombinant anti-human-IL-1 beta Antibody (Canakinumab Biosimilar)
Produktgrößen
100 µg
£550,00
12-9112-100UG
Über dieses Produkt
- SKU:
- 12-9112
- Zusätzliche Namen:
- Interleukin-1 beta; Catabolin
- Klonalität:
- Monoclonal
- Weitere Details:
- Target: IL-1 Beta Generic name: Canakinumab Product Origin: Recombinant in Human cells Canakinumab is a recombinant; human anti-human-IL-1-² monoclonal antibody that belongs to the IgG1/-º isotype subclass with a molecular mass of 145157 Daltons when deglycosylated. Canakinumab binds to human IL-1-² and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors; but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra). References: 1. Church LD; McDermott MF: Canakinumab; a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders. Curr Opin Mol Ther. 2009 Feb;11(1):81-89. 2. Lachmann HJ; et al.: Use of canakinumab in the cryopyrin-associated periodic syndrome. N Engl J Med. 2009 Jun 4;360(23):2416-25. doi:10.1056/NEJMoa0810787
- Format:
- Purified
- Isotyp:
- human IgG1
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:12-9112-ELISA.jpg
