Biotinylated Anti-41BB Ligand antibody(DM68); Rabbit mAb
Produktgrößen
100 µg
£1001,00
12-9054-B-100UG
Über dieses Produkt
- SKU:
- 12-9054-B
- Zusätzliche Namen:
- 4-1BB Ligand;TNFSF9;CD137L;CD137 L;CD137-L;41BBL;4-1BBL;41BB-L;
- translate.label.attr.clone:
- DM68
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB; which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene; TNFSF9/4-1BBL; has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines; and is thought to be involved in T cell-tumor cell interaction.
- Format:
- Liquid
- Host:
- Rabbit
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2 [o]C-8 [o]C for 6 months
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php