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Antikörper

Anti-4-1BB antibody(DM67); Rabbit mAb

Produktgrößen
100 µg
£801,00
12-9053-100UG
Über dieses Produkt
SKU:
12-9053
Zusätzliche Namen:
TNFRSF9; 41BB; CD137; CDw137; ILA;
translate.label.attr.clone:
DM67
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion; survival; and development of T cells. It can also induce proliferation in peripheral monocytes; enhance T cell apoptosis induced by TCR/CD3 triggered activation; and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Host:
Rabbit
Aufreinigung:
Purified from cell culture supernatant by affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human 4-1BB (B) were surface stained with Rabbit anti-4-1BB monoclonal antibody 1µg/ml (clone: DM67) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 4. Affinity ranking of different Rabbit anti-4-1BB mAb clones by titration of different concentration onto Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 4. Affinity ranking of different Rabbit anti-4-1BB mAb clones by titration of different concentration onto Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.