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Antikörper

Anti-CD27 antibody(DM58); Rabbit mAb

Produktgrößen
100 µg
£801,00
12-9045-100UG
Über dieses Produkt
SKU:
12-9045
Zusätzliche Namen:
CD27; TNFRSF7; S152; T14; Tp55
translate.label.attr.clone:
DM58
Klonalität:
Monoclonal
Weitere Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70; and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA); a proapoptotic protein; can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Host:
Rabbit
Immunogen:
Recombinant human CD27 (Ala20-Arg191) produced by using human HEK293 cells
Isotyp:
Rabbit IgG
Aufreinigung:
Purified from cell culture supernatant by affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2. FACS data of serially titrated Rabbit anti-CD27 monoclonal antibody (clone: DM58) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 3. Affinity ranking of different Rabbit anti-CD27 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
Figure 3. Affinity ranking of different Rabbit anti-CD27 mAb clones by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.