Anti-CTLA-4 antibody(DM51); Rabbit mAb
Produktgrößen
100 µg
£801,00
12-9041-100UG
Über dieses Produkt
- SKU:
- 12-9041
- Zusätzliche Namen:
- CTLA4; CD152
- translate.label.attr.clone:
- DM51
- Klonalität:
- Monoclonal
- Weitere Details:
- Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3; Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets; and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA; binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion; enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
- Host:
- Rabbit
- Immunogen:
- Recombinant human CTLA4 (Gln36-Ser161) produced by using human HEK293 cells
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
