Anti-CD38 antibody(DM28); Rabbit mAb
Produktgrößen
100 µg
£801,00
12-9019-100UG
Über dieses Produkt
- SKU:
- 12-9019
- Zusätzliche Namen:
- T10; cADPr hydrolase 1
- translate.label.attr.clone:
- DM28
- Klonalität:
- Monoclonal
- Weitere Details:
- CD antigen CD38 is also known as ADP-ribosyl cyclase 1; which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses; metabolic disturbances; and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection; leukemias; myelomas; solid tumors; type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
- Host:
- Rabbit
- Immunogen:
- Recombinant human CD38 (Val43-IIe300) produced by using human HEK293 cells
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Purified from cell culture supernatant by affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C for 12 months (Avoid repeated freezing and thawing)
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
