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Antikörper

Biotinylated Anti-CD38 antibody(DM28); Rabbit mAb

Produktgrößen
100 µg
£1001,00
12-9019-B-100UG
Über dieses Produkt
SKU:
12-9019-B
Zusätzliche Namen:
T10; cADPr hydrolase 1
translate.label.attr.clone:
DM28
Klonalität:
Monoclonal
Weitere Details:
CD antigen CD38 is also known as ADP-ribosyl cyclase 1; which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses; metabolic disturbances; and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection; leukemias; myelomas; solid tumors; type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Format:
Powder
Host:
Rabbit
Aufreinigung:
Purified from cell culture supernatant by affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2 [o]C-8 [o]C for 6 months
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody