Anti-SARS-CoV-2 Spike (Clone: 2143) Purified No Carrier Protein
Produktgrößen
100 µg
£810,00
12-8431-100UG
500 µg
£1222,00
12-8431-500UG
Über dieses Produkt
- SKU:
- 12-8431
- Zusätzliche Namen:
- COV2-2143; SARS-CoV-2 Spike Antibody
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: Anti-SARS-CoV-2 Spike; clone 2143; specifically targets an epitope on the SARS-CoV-2 full length Spike protein (not specific to RBD or NTD). Antigen Distribution: The spike is expressed on the surface of SARS-CoV-2. Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); the causative agent of coronavirus disease 2019 (COVID-19); is an enveloped; single-stranded; positive-sense RNA virus that belongs to the Coronaviridae family 1. The SARS-CoV-2 genome; which shares 79.6% identity with SARS-CoV; encodes four essential structural proteins: the spike (S); envelope (E); membrane (M); and nucleocapsid protein (N) 2. The S protein is a transmembrane; homotrimeric; class I fusion glycoprotein that mediates viral attachment; fusion; and entry into host cells 3. Each ~180 kDa monomer contains two functional subunits; S1 (~700 a.a) and S2 (~600 a.a); that mediate viral attachment and membrane fusion; respectively. S1 contains two major domains; the N-terminal (NTD) and C-terminal domains (CTD). The CTD contains the receptor-binding domain (RBD); which binds to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells 3-5.
- Isotyp:
- Human IgG1
- Aufreinigung:
- Purity :>=90% monomer by analytical SEC and SDS-PagePreparation : Recombinant antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are pu
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- This antibody may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php