Anti-Respiratory Syncytial Virus (RSV)
Produktgrößen
250 µg
£680,00
12-8412-250UG
Über dieses Produkt
- SKU:
- 12-8412
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: This monoclonal antibody recognizes respiratory syncytial virus (Clone RSV-78952) and is specific for the fusion protein of RSV Types A&B. These antibodies are non-reactive with: Influenza A & B; Adenovirus; Para 1-3; Measles; Mumps Background: Respiratory syncytial virus (RSV) is a common respiratory virus that infects the majority of children by two years old1; 2. While usually mild; RSV can be serious in infants and older adults and is the leading cause of bronchiolitis and pneumonia in children less than one year of age in the United States1. A related pneumovirus; human metapneumovirus (hMPV); also significantly contributes to hospitalizations resulting from lower respiratory tract infection2. Antibodies have been described that bind and neutralize both RSV and hMPV fusion (F) proteins. RSV F protein is a type I integral membrane protein that is synthesized as a 574 amino acid inactive precursor; assembled into a trimer; post-translationally modified; then cleaved to produce F1; F2; and intervening peptide pep273. Functional F protein has both pre- and post-fusion conformations. RSV F protein is highly conserved among RSV isolates from both A and B subgroups3 and is the primary target for antiviral drug development3 with several antigenic regions capable of introducing neutralizing antibodies2. RSV and hMPV F protein share ~36% sequence similarity.
- Host:
- Mouse
- Aufreinigung:
- Purity :>90% monomer by analytical SEC and SDS-PagePreparation : This monoclonal antibody is purified using a multi-step process; including the use of protein A or G to ensure extremely low levels of
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- This product contains no stabilizing proteins and should be stored at 2-8[o]C until ready to use.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Viral Particles
- Datenblatt des Herstellers:download_pdf.php