Anti-Enterovirus 68; Capsid (Clone EV-D68-105) Purified No Carrier Protein
Produktgrößen
250 µg
£583,00
12-8400-250UG
1 mg
£812,00
12-8400-1MG
Über dieses Produkt
- SKU:
- 12-8400
- Zusätzliche Namen:
- EVD68; Enterovirus; VP
- translate.label.attr.clone:
- EV-D68-105
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: Clone EV-D68-105 is a human IgG monoclonal antibody specifically binds to the capsid of Enterovirus D68 from clades B and D. Antigen Distribution: EV-D68 can be found in human respiratory epithelial cells; gastrointestinal cells; and motor neurons within the spinal cord's grey matter?. Background: EV-D68 is a highly transmissible respiratory disease that primarily impacts children. It is among the 100-plus non-polio enteroviruses and is listed as a NIAID Biodefense Priority Pathogen. The respiratory condition can vary from mild (resembling a common cold) to more severe; potentially resulting in acute flaccid myelitis (AFM); a condition characterized by lasting muscle weakness. The majority of individuals with EV-D68 encounter mild symptoms and recuperate without significant complications1. No vaccines are currently accessible for preventing EV-D68 infections; but practical measures can aid in lowering the chances of transmission. The virus is transmitted via respiratory secretions (saliva; nasal mucus; and sputum) when an infected individual coughs; sneezes or makes contact with surfaces subsequently touched by others2. Clone EV-D68-105 specifically binds to at least one of the VP proteins of the EV-D68 capsid. The capsid is made up of four viral proteins (VP1; VP2; VP3; and VP4) that are crucial for the virus's ability to bind and enter host cells. Clone EV-D68-48 clone effectively bind and neutralize the virus; specifically the clinically relevant clades B and D; preventing it from infecting cells and spreading4.
- Isotyp:
- Human IgG1
- Aufreinigung:
- Purity :>=90% monomer by analytical SEC and SDS-PagePreparation : Recombinant antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are pu
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- This antibody may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php