Anti-Zika; Env (Clone ZIKA-9670)-Purified No Carrier Protein
Produktgrößen
250µg
£680,00
12-8294-250UG
Über dieses Produkt
- SKU:
- 12-8294
- Zusätzliche Namen:
- Envelope; E protein
- translate.label.attr.clone:
- ZIKA-9670
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: Anti-Zika virus (Clone ZIKA-9670) is specific for Zika virus envelope (E) protein. Background: Zika virus (ZIKV) infection during pregnancy is a global public health problem 1; linked causally to severe fetal abnormalities 2. Prophylactic antibodies may prove useful in treating pregnant patients or for designing epitope-specific vaccines 1. ZIKV is a mosquito-transmitted flavivirus that encodes a single polyprotein with an ~11 kb positive-sense RNA open reading frame 1. The polyprotein is cleaved into seven non-structural (NS) proteins and three structural proteins (capsid (C); pre-membrane (prM); and envelope (E)). C forms a nucleocapsid. prM complexes with E to facilitate folding and prevent premature fusion to host membranes. E is responsible for viral assembly; attachment; entry; and fusion 1;3 and is a major target of neutralizing antibody research 3. Mature ZIKV virions incorporate 180 copies each of the E and M proteins 4;5.
- Host:
- Mouse
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purity: Preparation: This monoclonal antibody is purified by ion exchange chromatography.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- This purified antibody is stable when stored at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php