Anti-Shigella flexneri?2a; LPS (SHIG-3914)
Produktgrößen
250µg
£680,00
12-8264-250UG
Über dieses Produkt
- SKU:
- 12-8264
- translate.label.attr.clone:
- SHIG-3914
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: Anti-Shigella flexneri (Clone SHIG-3914) is specific for the LPS of Shigella flexneri 2a and displays no cross reactivity for Shigella flexneri 1a; 3a; 4a; 5a; 6; S. sonnei; S. dysenteriae; S. boydii; Citrobacter; Salmonella (mix) or E. coli (mix). Background: Shigella flexneri serotype 2a is a specific strain of Shigella flexneri responsible for causing shigellosis; a prominent global gastrointestinal infection. Serotype 2a holds clinical importance due to its prevalence and virulence. Shigella flexneri 2a infections often lead to severe symptoms such as bloody diarrhea; abdominal cramps; and fever1. The lipopolysaccharides (LPS) on the bacterial cell surface play a pivotal role in its pathogenicity by contributing to adhesion; immune evasion; and triggering inflammatory responses in the host. The bacterium's ability to invade the colonic epithelium leads to localized inflammation and tissue damage; causing the characteristic symptoms of shigellosis. Recently; there have been reports of increased transmission of extensively drug-resistant (XDR) Shigella spp. through sexual activity2.
- Host:
- Mouse
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purity: ≥90% Preparation: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- This purified antibody is stable when stored at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Toxins
- Datenblatt des Herstellers:download_pdf.php