Anti-Chikungunya Virus (Clone: CHKV-24)
Produktgrößen
100 µg
£649,00
12-8138-100UG
Über dieses Produkt
- SKU:
- 12-8138
- Zusätzliche Namen:
- CHKV
- translate.label.attr.clone:
- CHKV-24
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity : CHKV-24 targets the CHIKV E2 glycoprotein. Antigen Distribution : E2 glycoprotein is expressed on the surface of CHIKV. Background : Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes epidemics globally and has been declared a notable disease by the CDC. Symptoms include high fever; myalgia; rash; and severe polyarthritis which can persist for long after acute infection. CHIKV is an enveloped virus with an 11.8-kb single-stranded; positive-sense RNA genome with two open reading frames. There are three main genotypes; having 95.2 to 99.8% amino acid identity: Asian; West African; and East/Central/South African (ECSA). The mature CHIKV virion is comprised of a nucleocapsid protein C and two glycoproteins; E1 and E2. E1 participates in virus fusion. E2 functions in attachment to cells. E1 and E2 form 80 trimeric spikes on the virus surface. Co-circulation of CHIKV with other arboviruses; such as dengue; Zika; Mayaro; and yellow fever; occurs in many countries; posing significant difficulties for diagnosis. Monoclonal antibodies (MAb) can be used both for diagnosis and as a therapeutic agent. CHIKV can be rapidly detected by an immunochromatographic assay using MAbs against the CHIKV envelope protein.
- Host:
- Human
- Immunogen:
- B cells of a survivor of natural CHIKV infection
- Isotyp:
- Human IgG1
- Aufreinigung:
- >=95% monomer by analytical SEC
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Functional grade preclinical antibodies may be stored sterile as received at 2-8[o]C for up to one year. For longer term storage; aseptically aliquot in working volumes without diluting and store at >= -70[o]C. Avoid Repeated Freeze Thaw Cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Viral Particles
- Datenblatt des Herstellers:download_pdf.php