Anti-Ross River Virus (Clone: RRV-12)
Produktgrößen
100 µg
£649,00
12-8132-100UG
Über dieses Produkt
- SKU:
- 12-8132
- Zusätzliche Namen:
- RRV
- translate.label.attr.clone:
- RRV-12
- Klonalität:
- Monoclonal
- Weitere Details:
- Reactivity Species : Ross River-Virus Expression Host :HEK-293 Endotoxin Level :≤ 1.0 EU/mg as determined by the LAL method Specificity: RRV-12 activity is directed against the E2 protein. Antigen Distribution : RoE2 is expressed on the surface of RRV. Background : Ross River Virus (RRV) is a mosquito-borne; positive sense; single-stranded virus endemic to Australia and Papua New Guinea that belongs to the arthritogenic group of alphaviruses1. The mature glycoprotein is composed of E1 and E2 envelope proteins in a heterodimer; expressed as a trimeric spike on the virus surface . B cells were transformed with Epstein-Barr virus and then screened by direct virus binding ELISA. Hybridoma lines were established and mAbs were purified by single-cell flow cytometric sorting. Clone RRV-12 is of the IgG1 isotype and is capable of binding and incompletely neutralizing prototype strain RRV T48 in a focus reduction neutralization test.
- Host:
- Human
- Immunogen:
- A panel of human mAbs; including clone RRV-12; were sequenced from the peripheral blood mononuclear cells of two donors who were naturally infected with RRV
- Isotyp:
- Human IgG1
- Aufreinigung:
- >=95% monomer by analytical SEC
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Functional grade preclinical antibodies may be stored sterile as received at 2-8[o]C for up to one year. For longer term storage; aseptically aliquot in working volumes without diluting and store at >= -70[o]C. Avoid Repeated Freeze Thaw Cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Viral Particles
- Datenblatt des Herstellers:download_pdf.php