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Antikörper

Anti-Human DR5 (Drozitumab) Dylight® 488

Produktgrößen
100 µg
£760,00
12-8062-100UG
Über dieses Produkt
SKU:
12-8062
Zusätzliche Namen:
DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
translate.label.attr.clone:
PRO95780
Klonalität:
Monoclonal
Weitere Details:
Expression Host : HEK-293 This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Drozitumab. Clone PRO95780 recognizes human death receptor 5 (DR5). This product is for research use only. Drozitumab is a monoclonal antibody that specifically binds to human DR5. DR5 is expressed in a variety of solid tumors and hematologic malignancies; which are characteristically resistant to apoptosis. Drozitumab is a proapoptotic receptor agonists (PARA) that induces apoptosis in a variety of human cancer cell lines and xenograft models; both alone and in tandem with other antineoplastic agents.1 Apoptosis of cancer cells triggered by the activation of DR5; occurs without affecting most normal cell types. Anti-Human DR5 (Drozitumab) utilizes the same variable regions from the therapeutic antibody Drozitumab making it ideal for research projects.
Host:
Human
Immunogen:
DR5 scFv
Isotyp:
Human IgG1lambda
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
This DyLight® 488 conjugate is stable when stored at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody