Anti-Human DR5 (Drozitumab)
Produktgrößen
50 µg
£540,00
12-8060-50UG
100 µg
£760,00
12-8060-100UG
Über dieses Produkt
- SKU:
- 12-8060
- Zusätzliche Namen:
- DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
- translate.label.attr.clone:
- PRO95780
- Klonalität:
- Monoclonal
- Weitere Details:
- Expression Host : HEK-293 Pathogen Testing : To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens; all of this recombinant biosimilar antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile. This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Drozitumab. Clone PRO95780 recognizes human death receptor 5 (DR5). This product is for research use only. Drozitumab is a monoclonal antibody that specifically binds to human DR5. DR5 is expressed in a variety of solid tumors and hematologic malignancies; which are characteristically resistant to apoptosis. Drozitumab is a proapoptotic receptor agonists (PARA) that induces apoptosis in a variety of human cancer cell lines and xenograft models; both alone and in tandem with other antineoplastic agents.1 Apoptosis of cancer cells triggered by the activation of DR5; occurs without affecting most normal cell types. Anti-Human DR5 (Drozitumab) utilizes the same variable regions from the therapeutic antibody Drozitumab making it ideal for research projects.
- Host:
- Human
- Immunogen:
- DR5 scFv
- Isotyp:
- Human IgG1lambda
- Aufreinigung:
- >=95% monomer by analytical SEC
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Functional grade biosimilar antibodies may be stored sterile as received at 2-8[o]C for up to one month. For longer term storage; aseptically aliquot in working volumes without diluting and store at -80[o]C. Avoid Repeated Freeze Thaw Cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php