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Antikörper

Phospho-c-Fos (Ser32) (Clone: BA9) rabbit mAb

Produktgrößen
20 µl
£631,00
12-4328-20UL
200 µl
£1021,00
12-4328-200UL
Über dieses Produkt
SKU:
12-4328
Zusätzliche Namen:
Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7; G0S7
translate.label.attr.clone:
cFosS32-BA9
Klonalität:
Monoclonal
Konjugat:
Unconjugated
Weitere Details:
c-FOS belongs to the Fos family of nuclear oncogenes which include Fos B; Fos-related antigen 1 (FRA1); Fos-related antigen 2 (FRA2) in addition to c-Fos(1). Activator Protein-1 (AP-1) is formed upon dimerization of Fos proteins with Jun protiens (c-Jun; Jun B; and JunD)(2;3). AP-1 is considered a transcription factor that binds to TRE/AP-1 elements and activates transcription. ERK5 is involved with c-Fos phosphorylation at Ser32 and Thr232 which increase c-Fos stability and its nuclear translocation.
Format:
Purified
Host:
Rabbit
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser32 of human phospho c-Fos
Isotyp:
Rabbit IgG1k
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Fig 2 : Peptide blocking flow cytometric analysis of HeLa cells secondary antibody only negative control (light blue) or untreated (red) or treated with UV + TPA (green) or untreated and blocked with phospho-peptide (black) or treated and blocked with phospho peptide (gold) or untreated and blocked with non-phospho peptide (dark blue) or treated and blocked with non-phospho peptide (purple) using Phospho-c-Fos (Ser32) antibody cFosS32-BA9 at 0.01µg/mL.
Fig-3: Flow cytometric analysis of L929 cells; secondary antibody only negative control (blue) or untreated (red) or treated with UV (green) using Phospho-c-Fos (Ser32) antibody cFosS32-BA9 at 0.001 µg/mL.
Fig-4: Flow cytometric analysis of C6 cells; secondary antibody only negative control (blue) or untreated (red) or treated with UV+TPA (green) using Phospho-c-Fos (Ser32) antibody cFosS32-BA9 at 0.001 µg/mL.
Fig-4: Flow cytometric analysis of C6 cells; secondary antibody only negative control (blue) or untreated (red) or treated with UV+TPA (green) using Phospho-c-Fos (Ser32) antibody cFosS32-BA9 at 0.001 µg/mL.