Phospho-Stat6 (Tyr641) (Clone: G12) rabbit mAb APC conjugate
Produktgrößen
10 Tests
£532,00
12-4143-10TESTS
100 Tests
£792,00
12-4143-100TESTS
Über dieses Produkt
- SKU:
- 12-4143
- Zusätzliche Namen:
- Signal transducer and activator of transcription 6; IL-4 Stat
- translate.label.attr.clone:
- Stat6Y641-G12
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- The transcription factor Stat6 is a member of the signal transducers and activators of transcription (STAT) family of proteins. Stat6 is the only member of this family that is activated by interleukin-4 (IL-4); after which Stat6 is both tyrosine- and serine-phosphorylated by Jak kinases. The consensus Stat6 binding site TTCN4GAA is found in the promoters of many genes regulated by IL-4. In T lymphocytes; Stat6 is required for differentiation into Th2 cells in response to IL-4. Stat6 may play a role in solid tumorigenesis; a large immunohistochemistry study of Stat6 expression in over 2;000 tumor samples confirmed strong nuclear staining.
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
- Isotyp:
- Rabbit IgG1k
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg