Phospho-MET(Tyr1234/1235) (Clone: 6F11) rabbit mAb PE conjugate
Produktgrößen
10 Tests
£532,00
12-4102-10TESTS
100 Tests
£792,00
12-4102-100TESTS
Über dieses Produkt
- SKU:
- 12-4102
- Zusätzliche Namen:
- AUTS9; c-Met; Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; HGFR; MET; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; oncogene MET; Proto-oncogene c-Met; RCCP2; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met
- translate.label.attr.clone:
- MetY12341235-6F11
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- c-Met; also called tyrosine-protein kinase MET or hepatocyte growth factor receptor (HGFR); has tyrosine kinase activity (1). MET is a single pass tyrosine kinase receptor essential for embryonic development; organogenesis and wound healing. Normally; MET is expressed only in stems cells and progenitor cells but excessive expression of MET/HGFR and its autocrine activation by co-expression of hepatocyte growth factor (HGF) ligand are implicated in oncogenesis (2;3). Aberrantly activated MET leads to tumor growth; angiogenesis; and cancer metastasis and is correlated with poor prognosis. Abnormal activation of MET is observed in various human malignancies; such as kidney; liver; stomach; breast; and brain. MET activation by HGF induces MET kinase catalytic activity and leads to phosphorylation at Tyr 1234 and Tyr 1235.
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Tyr1234/Tyr1235 of human phospho Met
- Isotyp:
- Rabbit IgG1k
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg