Phospho-Histone H2A.X (Ser139) (Clone: 1B3) rabbit mAb FITC conjugate
Produktgrößen
100 tests
£748,00
12-4095-100TESTS
Über dieses Produkt
- SKU:
- 12-4095
- Zusätzliche Namen:
- H2AFX; H2AX; ?H2AX; gamma-H2AX
- translate.label.attr.clone:
- HisH2AXS139-1B3
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- Histone H2AX is a variant of the nucleosome core histone H2A and is phosphorylated at Ser139 in response to DNA damage. Histone H2AX phosphorylation is considered a specific reporter of double-strand DNA breaks. The protein is also referred to as gH2AX when phosphorylated at Ser139. H2AX phosphorylation is especially strong in response to double-strand breaks formed during apoptosis. However; physiological phosphorylation of Histone H2AX occurs when double-strand DNA breaks are formed during meiosis and V(D)J recombination. A549 and DU145 cell lines have been found to have higher expression levels of phosphorylated Histone H2AX compared to Jurkat; MCF-7; or HL-60 cell lines.
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho histone H2A.X.
- Isotyp:
- Rabbit IgG1k
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg