Phospho-Histone H3 (Ser28) (Clone: D6) rabbit mAb APC conjugate
Produktgrößen
10 Tests
£532,00
12-4049-10TESTS
100 Tests
£792,00
12-4049-100TESTS
Über dieses Produkt
- SKU:
- 12-4049
- Zusätzliche Namen:
- Histone H3.1t; H3t; H3FT; HIST3H3
- translate.label.attr.clone:
- HisH3S28-D6
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- Histones are highly conserved proteins that serve the core of nucleosomes; which serve to organize chromatin fiber for DNA packing. Histone H3 phosphorylation plays a major role in both transcriptional activation; which requires unpacking of the chromatin structure; and in chromosome packing during cell division. Histone H3 is phosphorylated at residues Ser10 and Ser28; and is acetylated at Lys14. Phosphorylation at Ser10 occurs during entry into mitosis prior to chromatin condensation; and phosphorylation at Ser28 follows a similar pattern. In response to EGF stimulation; it has been proposed that sequential Ser10 phosphorylation; then Lys14 acetylation occurs; causing a change in chromatin structure and gene activation.
- Format:
- Conjugated
- Host:
- Rabbit
- Immunogen:
- A synthetic phospho-peptide corresponding to residues surrounding Ser28 of human phospho Histone H3
- Isotyp:
- Rabbit IgG1k
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg