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Antikörper

Anti-Thyroglobulin (Thyroidal Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:r6E1)

Produktgrößen
20 µg
£408,00
12-1250-20UG
100 µg
£716,00
12-1250-100UG
Über dieses Produkt
SKU:
12-1250
Zusätzliche Namen:
AITD3; hTG; TDH3; Tg; Tgn
translate.label.attr.clone:
r6E1
Klonalität:
Monoclonal
Weitere Details:
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. iPrior to forming dimers; thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. iThe vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even thoµgh sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin; combined with anti-calcitonin; can identify medullary carcinomas of the thyroid. Furthermore; anti-thyroglobulin; combined with anti-TTF1; can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Format:
Purified
Host:
Mouse
Immunogen:
Human thyroid follicular cells
Isotyp:
Mouse IgG1; kappa
Aufreinigung:
Protein A/G
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg