Anti-p21WAF1 (Tumor Suppressor Protein) Recombinant Rabbit Monoclonal Antibody (Clone:CIP1/2275R)
Produktgrößen
20 µg
£408,00
12-1230-20UG
100 µg
£716,00
12-1230-100UG
Über dieses Produkt
- SKU:
- 12-1230
- Zusätzliche Namen:
- Activating Fragment 1; CAP20; CDK-interacting protein 1; CDKI; CDKN1; CDKN1A; CIP1; Cyclin-dependent kinase inhibitor 1A (p21; Cip1); DNA Synthesis Inhibitor; MDA6; Melanoma Differentiation Associated Protein 6; p21Cip1/Waf1; PIC1; SDI1; SLC12A9; Wild type p53 activated fragment 1 (WAF1)
- translate.label.attr.clone:
- CIP1/2275R
- Klonalität:
- Monoclonal
- Weitere Details:
- This MAb recognizes a 21kDa protein; identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type; but not mutant; p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma; non-small cell lung carcinoma; thyroid carcinoma).
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human CDKN1A protein
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A/G
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
