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Antikörper

Anti-MUC16 / CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:OCA125/2349R)

Produktgrößen
20 µg
£408,00
12-1216-20UG
100 µg
£716,00
12-1216-100UG
Über dieses Produkt
SKU:
12-1216
Zusätzliche Namen:
CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
translate.label.attr.clone:
OCA125/2349R
Klonalität:
Monoclonal
Weitere Details:
The mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large; secreted and cell surface glycoproteins crucial for adhesion modulation; signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4; Mucin 5 (AC and B); Mucins 6-8; Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125); encoded for by the gene MUC16; is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain; an extracellular domain and an amino terminal domain. Mucin 16; an ovarian cancer-associated antigen; is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
Format:
Purified
Host:
Rabbit
Immunogen:
Recombinant full-length human MUC16 protein
Isotyp:
Rabbit IgG
Aufreinigung:
Protein A/G
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg