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Antikörper

Anti-Cytokeratin 10 (Suprabasal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (Clone:KRT10/1948R)

Produktgrößen
20 µg
£408,00
12-1153-20UG
100 µg
£716,00
12-1153-100UG
Über dieses Produkt
SKU:
12-1153
Zusätzliche Namen:
BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
translate.label.attr.clone:
KRT10/1948R
Klonalität:
Monoclonal
Weitere Details:
This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
Format:
Purified
Host:
Rabbit
Immunogen:
Recombinant full-length of human KRT10 protein
Isotyp:
Rabbit IgG
Aufreinigung:
Protein A/G
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg