Anti-CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Recombinant Rabbit Monoclonal Antibody (Clone:CFTR/2290R)
Produktgrößen
20 µg
£408,00
12-1140-20UG
100 µg
£716,00
12-1140-100UG
Über dieses Produkt
- SKU:
- 12-1140
- Zusätzliche Namen:
- ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7); cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
- translate.label.attr.clone:
- CFTR/2290R
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 165-170kDa; identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD); two nucleotide-binding domains (NBD); and an R domain. It is structurally similar to multidrµg resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters; also known as traffic ATPases; which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3';5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas; airway; intestine; bile duct; sweat gland; and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human CFTR protein
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A/G
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
