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Antikörper

Anti-CD43 (T-Cell Marker) Recombinant Mouse Monoclonal Antibody (Clone:rSPN/839)

Produktgrößen
20 µg
£408,00
12-1113-20UG
100 µg
£716,00
12-1113-100UG
Über dieses Produkt
SKU:
12-1113
Zusätzliche Namen:
Galactoglycoprotein; GALGP; GPL115; Leukocyte sialoglycoprotein; Leukosialin; LSN; Sialophorin; SPN
translate.label.attr.clone:
rSPN/839
Klonalität:
Monoclonal
Weitere Details:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation); identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb rSPN/839; called "b" as opposed to "a" for rSPN/839. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma; especially a low-grade lymphoma; rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20; effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Format:
Purified
Host:
Mouse
Immunogen:
Human full-length recombinant CD43 protein
Isotyp:
Mouse IgG1; kappa
Aufreinigung:
Protein A/G
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg