Anti-Beta-2 Microglobulin (Renal Failure &Tumor Marker) Recombinant Mouse Monoclonal Antibody (Clone:rB2M/961)
Produktgrößen
20 µg
£408,00
12-1083-20UG
100 µg
£716,00
12-1083-100UG
Über dieses Produkt
- SKU:
- 12-1083
- Zusätzliche Namen:
- B2M; Beta 2 microglobin; Beta 2 microglobulin; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; Hdcma22p
- translate.label.attr.clone:
- rB2M/961
- Klonalität:
- Monoclonal
- Weitere Details:
- Recognizes a protein of 12kDa; identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alphaheavy chain that contains three subdomains (alpha1; alpha2; alpha3) and a non-covalent associating light chain; known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alphaheavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alphaheavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant Full length human B2M protein
- Isotyp:
- Mouse IgG2b; kappa
- Aufreinigung:
- Protein A/G
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
