Polyclonal Antibody to Mafa
Produktgrößen
25ug
£319,00
11-8065-25UG
100ug
£407,00
11-8065-100UG
Über dieses Produkt
- SKU:
- 11-8065
- Zusätzliche Namen:
- MAFA
- Klonalität:
- Polyclonal
- Weitere Details:
- Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.
- Format:
- Purified
- Gendetails:
- MAFA
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg