Polyclonal Antibody to E Cadherin
Produktgrößen
25ug
£319,00
11-7545-25UG
100ug
£407,00
11-7545-100UG
Über dieses Produkt
- SKU:
- 11-7545
- Zusätzliche Namen:
- CDH1||CDHE||UVO
- Klonalität:
- Polyclonal
- Weitere Details:
- E-cadherin is a calcium-regulated adhesion molecule expressed in most normal epithelial tissues. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. The E-cadherin gene is located on chromosome 16q22.1. E-cadherin is associated with gland formation, stratification, and epithelial polarization. Besides its role in normal cells, this highly conserved gene can play a major role in malignant cell transformation, and especially in tumor development and progression. Selective loss of E-cadherin can cause dedifferentiation and invasiveness in human carcinomas, leading E-cadherin to be classified as a tumor suppressor.
- Format:
- Purified
- Gendetails:
- CDH1
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant E-cadherin protein (amino acids 438-556) was used as the immunogen for this antibody .
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg