Polyclonal Antibody to IMPDHII
Produktgrößen
25ug
£319,00
11-3028-25UG
100ug
£407,00
11-3028-100UG
Über dieses Produkt
- SKU:
- 11-3028
- Zusätzliche Namen:
- IMPDH2||IMPD2
- Klonalität:
- Polyclonal
- Weitere Details:
- Human type II inosine monophosphate dehydrogenase (IMPDHII) is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. It is linked to cell growth, differentiation, and malignant transformation. IMPDHII also plays an important role in the negative regulation of TLR2 signaling by modulating PI3K activity. Indeed, IMPDHII increases the phosphatase activity of SHP1, which participates in the inactivation of PI3K. Enhanced expression of IMPDHII promotes the tumor metastasis and the advanced tumor progression in patients with prostate cancer.
- Format:
- Purified
- Gendetails:
- IMPDH2
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant IMPDHII protein (amino acids 86-291) was used as the immunogen for this antibody.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg