Polyclonal Antibody to TxNIP/VDUP1
Produktgrößen
25ug
£319,00
11-3023-25UG
100ug
£407,00
11-3023-100UG
Über dieses Produkt
- SKU:
- 11-3023
- Zusätzliche Namen:
- TXNIP||VDUP1
- Klonalität:
- Polyclonal
- Weitere Details:
- TXNIP (thioredoxin interacting protein) inhibits thioredoxin activity by limiting its bioavailability in response to oxidative stress. TXNIP restores COPS5-induced suppression of CDKN1B stability by interacting with COPS5 and blocks the COPS5-mediated translocation of CDKN1B from nucleus to the cytoplasm. TXNIP functions as a transcriptional repressor. TXNIP has been reported to be a suppressor of tumor cell growth and inhibits the proteasomal degradation of DDIT4, contributing to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). TXNIP is expresed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdale.
- Format:
- Purified
- Gendetails:
- TXNIP
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant TxNIP protein (amino acids 50-300) was used as the immunogen for this antibody.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:get_image.jpg