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Antikörper

Polyclonal Antibody to GAPDH

Produktgrößen
25ug
£216,00
11-13024-25UG
100ug
£407,00
11-13024-100UG
Über dieses Produkt
SKU:
11-13024
Zusätzliche Namen:
GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Klonalität:
Polyclonal
Weitere Details:
GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is an enzyme best known for its role in glycolysis. However, extra-glycolytic functions of GAPDH have been described, including regulation of protein expression via RNA binding. GAPDH binds to numerous AREs (adenine-uridine rich elements) from various mRNA 3'-untranslated regions in vitro and in vivo despite its lack of a canonical RNA binding motif. GAPDH specifically catalyzes the simultaneous phosphorylation and oxidation of glyceraldehyde 3-phosphate using NAD+ (Nicotinamide Adenine Dinucleotide) as a cofactor to produce glycerate 1,3-biphosphate and NADH. In addition to its role in energy production, GAPDH has been implicated in many cellular processes including DNA repair tRNA export, membrane fusion and transport, endocytosis and nuclear membrane assembly, and cell death.
Format:
Purified
Gendetails:
GAPDH
Host:
Rabbit
Immunogen:
A partial length recombinant GAPDH protein was used as the immunogen for this antibody.
Isotyp:
Rabbit IgG
Aufreinigung:
Protein A Chromatography
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Hersteller:
Abeomics
Typ:
Antibodies:Polyclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure-2: Western blot analysis of GAPDH. Anti- GAPDH antibody (11-13024) was used at 1 µg/ml on (1) r Brain; (2) r Heart; (3) r Kidney; (4) r Liver; (5) r Lung; (6) r Skeletal Muscle; (7) r Stomach; (8) r Spleen; (9) r Ovary; (10) r Testis lysates.
Figure-3: Western blot analysis of GAPDH. Anti- GAPDH antibody (11-13024) was used at 1 µg/ml on (1) m Kidney; (2) m Liver; (3) m Lung; (4) m Skeletal Muscle and (5) m Testis lysates.
Figure-4: Western blot analysis of GAPDH. Anti- GAPDH antibody (11-13024) was used at 1 µg/ml on (1) 3T3; (2) Hela; (3) Jurkat; (4) PC3; (5) HCT-116; (6) Snu1 and (7) PANC-1 lysates.
Figure-4: Western blot analysis of GAPDH. Anti- GAPDH antibody (11-13024) was used at 1 µg/ml on (1) 3T3; (2) Hela; (3) Jurkat; (4) PC3; (5) HCT-116; (6) Snu1 and (7) PANC-1 lysates.
Figure-5: Western blot analysis of GAPDH. Anti- GAPDH antibody (11-13024) was used at 1 µg/ml on (1) K562; (2) A549; (3) MCF-7; (4) 293; (5) A431 and (6) HepG2 lysates.