Polyclonal Antibody to HOXA9
Produktgrößen
25ug
£319,00
11-12020-25UG
100ug
£407,00
11-12020-100UG
Über dieses Produkt
- SKU:
- 11-12020
- Zusätzliche Namen:
- HOXA9||HOX1G
- Klonalität:
- Polyclonal
- Weitere Details:
- HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.
- Format:
- Purified
- Gendetails:
- HOXA9
- Host:
- Rabbit
- Immunogen:
- A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg