Polyclonal Antibody to Survivin
Produktgrößen
25ug
£319,00
11-1006-25UG
100ug
£407,00
11-1006-100UG
Über dieses Produkt
- SKU:
- 11-1006
- Zusätzliche Namen:
- BIRC5||API4||IAP4
- Klonalität:
- Polyclonal
- Weitere Details:
- Survivin is the smallest mammalian member of the IAP (Inhibitor-Of-Apoptosis) gene family. It regulates two essential cellular processes; inhibits apoptosis and promotes cell proliferation. Survivin also plays a main role in cancer progression because it prevents apoptosis by inhibition of caspase 3 and caspase 7, and by regulating the G2 and M phases of the cell cycle. Overexpression of survivin is associated with neoplasia and metastasis. Survivin might be used as a biomarker and a primary chemotherapeutic target for the detection and treatment of gastrointestinal tract cancer, especially esophageal, gastric, and colon cancers.
- Format:
- Purified
- Gendetails:
- BIRC5
- Host:
- Rabbit
- Immunogen:
- Full length recombinant Survivin protein was used as the immunogen for this antibody.
- Isotyp:
- Rabbit IgG
- Aufreinigung:
- Protein A Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Polyclonal Antibody
- Datenblatt des Herstellers:1.jpg