Monoclonal Antibody to Mouse PD-L1 (Clone: 10F.9G2)
Produktgrößen
25ug
£319,00
10-7648-25UG
100ug
£429,00
10-7648-100UG
Über dieses Produkt
- SKU:
- 10-7648
- Zusätzliche Namen:
- Programmed cell death 1 ligand 1; Programmed cell death 1 ligand 1; Programmed death ligand 1; B7-H1
- translate.label.attr.clone:
- 10F.9G2
- Klonalität:
- Monoclonal
- Weitere Details:
- PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belonging to the B7 superfamily that inhibits immune responses through its receptor, PD-1. PD-L1 plays a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells, and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274/PD-L1 have been reported during bacterial infection, inflammation, and in numerous autoimmune diseases.
- Format:
- Purified
- Gendetails:
- Cd274
- Host:
- Rat
- Immunogen:
- Mouse CD274
- Isotyp:
- Rat IgG2b, k
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:10-7648 FLOW.jpg