Monoclonal Antibody to PAPP-A (Clone: ABM4C62)
Produktgrößen
25ug
£319,00
10-7569-25UG
100ug
£429,00
10-7569-100UG
Über dieses Produkt
- SKU:
- 10-7569
- Zusätzliche Namen:
- Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 proteas; Pregnancy-associated plasma protein A
- translate.label.attr.clone:
- ABM4C62
- Klonalität:
- Monoclonal
- Weitere Details:
- PAPP-A (pregnancy-associated plasma protein A) is a zinc metalloproteinase in the insulin-like growth factor system that is expressed by tissues outside of pregnancy and involved in normal and dysregulated growth. It has prognostic impact in pregnancy and acute coronary syndrome. PAPP-A regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. PAPP-A levels is associated with abnormal glucose metabolism and increased risk of atherosclerosis in AGHD (Adult Growth Hormone Deficiency) patients.
- Format:
- Purified
- Gendetails:
- PAPPA
- Host:
- Mouse
- Immunogen:
- A partial length recombinant PAPP-A protein (amino acids 332-561) was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG2b Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg