Monoclonal Antibody to Human PD-L1 (Clone: ABM4E54) PE Conjugated
Produktgrößen
100test
£429,00
10-7562-P-100TEST
Über dieses Produkt
- SKU:
- 10-7562-P
- Zusätzliche Namen:
- CD274||B7H1||PDCD1L1||PDCD1LG1||PDL1
- translate.label.attr.clone:
- ABM4E54
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belonging to the B7 superfamily that inhibits immune responses through its receptor, PD-1. PD-L1 plays a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells, and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitates apoptosis of activated T cells, and induces T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation, and in numerous autoimmune diseases.
- Format:
- Purified
- Gendetails:
- CD274
- Host:
- Mouse
- Immunogen:
- A partial length recombinant PDL1 protein (amino acids 18-227) was used as the immunogen for this antibody.
- Isotyp:
- Mouse IgG2a Kappa
- Aufreinigung:
- Protein G Chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store the antibody at 4[o]C; stable for 6 months.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:10-7562-P.jpg